Brief ReportAn Evaluation of Irreversible Psychosurgical Treatment of Patients With Obsessive-Compulsive Disorder in the Netherlands, 2001–2008van Vliet, I.M.*†; van Well, E.P.L.*; Bruggeman, Richard†‡; Campo, Joost á†§; Hijman, R.†∥; van Megen, H.J.G.M.†¶; van Balkom, A.J.L.M.†#; van Rijen, P.C.∥Author Information *Department of Psychiatry, Leiden University Medical Center (LUMC), Leiden, the Netherlands; †Working Group for Indication Psychosurgery in the Netherlands (WIPN), the Netherlands; ‡University Medical Center Groningen, Groningen, the Netherlands; §Mondriaan ZorgGroep; ∥University Medical Center Utrecht, Utrecht, the Netherlands; ¶GGZ Central in Ermelo, the Netherlands; and #GGZ InGeest and VU-University Medical Centre, Amsterdam, the Netherlands. Dr R. Hijman is now retired. Send reprint requests to E.P.L. van Well, Department of Psychiatry B1-P, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden, the Netherlands. E-mail: [email protected]. The Journal of Nervous and Mental Disease: March 2013 - Volume 201 - Issue 3 - p 226-228 doi: 10.1097/NMD.0b013e3182848b15 Buy Metrics Abstract Admissions for irreversible psychosurgical treatment of obsessive-compulsive disorder (OCD) by the Working Group for Indication Psychosurgery in the Netherlands were analyzed, and the postsurgical effects on symptom severity and quality of life were evaluated. The data were extracted from patient records in the period 2001–2008, and there was a postoperative assessment with a semistructured interview. Fourteen patients applied, having severe OCD with mostly one or more comorbid disorders. The mean Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score was 32 points. Four of seven patients in whom psychosurgery was deemed useful were operated on. The decrease of the Y-BOCS score from registration to after surgery was 9 points (range, 3–17 points). An improvement in social function was present in three of four patients. In conclusion, psychosurgery can be a valuable treatment option for patients with severe OCD in whom other treatments fail. © 2013 Lippincott Williams & Wilkins, Inc.