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The Effects of Borderline Personality Disorder and Panic Disorder on Suicide Attempts and the Associated Influence of Affective Dysregulation in the General Population

Turnbull, Danielle L. BA (Hons)*; Cox, Brian J. PhD*†‡; Oleski, Janine MA*; Katz, Laurence Y. MD

The Journal of Nervous and Mental Disease: February 2013 - Volume 201 - Issue 2 - p 130–135
doi: 10.1097/NMD.0b013e31827f6449
Original Articles

Previous studies have demonstrated individual associations between borderline personality disorder (BPD), panic attacks (PAs), and panic disorder (PD) in relation to suicide attempts (SAs). This study examined the comorbid effects of these variables. Data from wave 2 of the National Epidemiologic Survey of Alcohol and Related Conditions (N = 34,653) were used to examine using logistic regression the relationship between individuals with BPD (n = 562), PA (n = 253), PD (n = 255), comorbid BPD and PD (n = 146), and co-occurring BPD and PA (n = 119) who had attempted suicide. It was found that BPD, PD, and PA are associated with SAs. Comorbid PD and BPD, or PA and BPD, only slightly increased the association of BPD alone with SA. Associations were greatly decreased after controlling for affective dysregulation. These findings emphasize the importance of affective dysregulation in individuals with BPD in relation to suicide attempts.

*Department of Psychology; †Department of Psychiatry; and ‡Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Send reprint requests to Brian J. Cox, PhD, PZ-432 PsycHealth Centre, 771 Bannatyne Ave, Winnipeg, Manitoba, Canada, R3E 3N4. E-mail:

© 2013 Lippincott Williams & Wilkins, Inc.