Original ArticlesThe Association Between Trauma and Chronic Medical Conditions in Individuals With Severe Mental IllnessRaab, Phillip Andrew MA; Claypoole, Keith Harvey PhD; Hayashi, Kentaro PhD; Baker, Charlene PhDAuthor Information University of Hawaii at Mānoa, Honolulu. Send reprint requests to Phillip Andrew Raab, MA, University of Hawaii at Mānoa, Department of Psychology, Sakamaki C 400, Honolulu, HI 96822-2294. E-mail: firstname.lastname@example.org. The Journal of Nervous and Mental Disease: October 2012 - Volume 200 - Issue 10 - p 897-903 doi: 10.1097/NMD.0b013e31826b9fda Buy Metrics Abstract Based on the concept of allostatic load, this study proposed and evaluated a model for the relationship between childhood trauma, chronic medical conditions, and intervening variables affecting this relationship in individuals with severe mental illness. Childhood trauma, adult trauma, major depressive disorder symptoms, posttraumatic stress disorder symptoms, health risk factors, and chronic medical conditions were retrospectively assessed using a cross-sectional survey design in a sample of 117 individuals with severe mental illness receiving public mental health services. Path analyses produced a good-fitting model, with significant pathways from childhood to adult trauma and from adult trauma to chronic medical conditions. Multisample path analyses revealed the equivalence of the model across sex. The results support a model for the relationship between childhood and adult trauma and chronic medical conditions, which highlights the pathophysiological toll of cumulative trauma experienced across the life span and the pressing need to prevent retraumatization in this population. © 2012 Lippincott Williams & Wilkins, Inc.