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Quality of Life in Community-Dwelling Patients With Schizophrenia in China

Xiang, Yu-Tao MD, PhD*†; Hou, Ye-Zhi MD*; Yan, Fang MD, PhD*; Dixon, Lisa B. MD; Ungvari, Gabor S. MD, PhD§; Dickerson, Faith PhD; Li, Weng-Yong MD; Li, Wen-Xiu MD#; Zhu, Yu-Ling MD**; Chan, Sandra S.M. MD; Lee, Edwin H.M. MD; Chiu, Helen F.K. MD

The Journal of Nervous and Mental Disease: July 2012 - Volume 200 - Issue 7 - p 584–587
doi: 10.1097/NMD.0b013e31825bfc71
Original Articles

The aim of this study was to assess Chinese schizophrenia patients’ quality of life (QOL) and identify its demographic and clinical correlates. A random sample of 540 community-dwelling schizophrenia patients was interviewed using standardized assessment instruments. The patients’ basic sociodemographic and clinical data and QOL were collected. Compared with the general population, patients had significantly lower scores in the physical and psychological QOL domains. Multivariate analyses showed that better social support independently predicted higher QOL in all domains, whereas more severe positive symptoms predicted worse psychological and environmental domains. Overall psychopathology predicted both worse physical and psychological domains; depressive symptoms and being married predicted worse physical and social QOL, respectively. Our results suggest that therapeutic and psychosocial interventions alleviating positive and depressive symptoms and improving poor social support and marriage-related problems in Chinese patients with schizophrenia might be of considerable benefit in improving their QOL.

*Beijing Anding Hospital, Capital Medical University, Beijing, China; †Department of Psychiatry, Chinese University of Hong Kong, Hong Kong; ‡Division of Services Research, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, MD; §The University of Notre Dame Australia/Marian Centre, Perth, Australia; ∥The Stanley Research Program at Sheppard Pratt, Baltimore, MD; ¶The Third Hospital of Chaoyang District; #Mental Healthcare Institution of Haidian District; and **Mental Healthcare Institution of Changping District, Beijing, China.

Y.-T.X, Y.-Z.H., and F.Y. contributed equally to this article.

This study was supported by grants from the Foundation of Capital Medical Development and Research (no. 2005-1001), the Beijing Bureau of Public Health Funds for Young Scholar (QN2008-003), the National Natural Science Foundation of China (no. 30800367; 81171270;), and the Beijing Nova Program of the Beijing Municipal Science and Technology Commission (no. 2008B59).

Send reprint requests to Yu-Tao Xiang, MD, PhD, Department of Psychiatry, Chinese University of Hong Kong, Ground Floor, Multicentre, Tai Po Hospital, Tai Po, NT, Hong Kong. E-mail:

© 2012 Lippincott Williams & Wilkins, Inc.