Original ArticleA Comparison of Contextual and Biomedical Models of Stigma Reduction for Depression With a Nonclinical Undergraduate SampleRusch, Laura C. MS; Kanter, Jonathan W. PhD; Brondino, Michael J. PhDAuthor Information From the Department of Psychology, University of Wisconsin–Milwaukee, Milwaukee, Wisconsin. Supported by a grant from the Center for Addiction and Behavioral Health Research to Jonathan Kanter. Send reprint requests to Jonathan W. Kanter, PhD, University of Wisconsin-Milwaukee, Department of Psychology, PO Box 413, Milwaukee, WI 53201. E-mail: [email protected]. The Journal of Nervous and Mental Disease: February 2009 - Volume 197 - Issue 2 - p 104-110 doi: 10.1097/NMD.0b013e318192416f Buy Metrics Abstract Stigma reduction programs are dominated by a biomedical model that presents depression as a medical illness. Alternately, a contextual model emphasizes that one should not be blamed for environmental influences. This study compared biomedical, contextual, and control stigma reduction programs to each other and to a no-program control. The main hypotheses were that the contextual program would have the greatest impact and that a match between participants’ beliefs about depression and the model presented would moderate this effect. Seventy-four participants were randomized to the 3 programs and 12 participants served as a no-program control. The contextual and control programs reduced stigma significantly compared with the no-program control, whereas the biomedical program did not. Beliefs about depression moderated this effect only for the biomedical condition. Contextual and control programs seem to be effective but a biomedical model may be risky for those who disagree with the model. Theoretical implications are discussed. © 2009 Lippincott Williams & Wilkins, Inc.