Original ArticlesCharacteristics and Predictors of Full and Partial Recovery From Generalized Anxiety Disorder in Primary Care PatientsRodriguez, Benjamin F. PhD*; Weisberg, Risa B. PhD†; Pagano, Maria E. PhD†; Bruce, Steven E. PhD†; Spencer, Michael A. PhD‡; Culpepper, Larry MD§; Keller, Martin B. MD† Author Information *Department of Psychology, Southern Illinois University at Carbondale, Carbondale, Illinois; †Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, Rhode Island; ‡Department of Economics, Minnesota State University at Mankato, Mankato, Minnesota; and §Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts. Drs. Risa B. Weisberg, Martin B. Keller, and Larry Culpepper have disclosed financial relationships with pharmaceutical companies. Detailed disclosure information is available from The Journal of Nervous and Mental Disease. The PCAP is supported by an unrestricted grant from Pfizer Pharmaceuticals, Inc. Portions of this paper were presented at the Annual Meetings of the Anxiety Disorders Association of America, Toronto, Ontario, Canada (March 2003), and Seattle, Washington (March 2005). Send reprint requests to Benjamin F. Rodriguez, PhD, Department of Psychology, Southern Illinois University, Mailcode 6502, Carbondale, IL 62901-6502. The Journal of Nervous and Mental Disease: February 2006 - Volume 194 - Issue 2 - p 91-97 doi: 10.1097/01.nmd.0000198140.02154.32 Buy Metrics Abstract The current study examined the naturalistic course of generalized anxiety disorder (GAD) in a sample of 113 primary care patients across a 2-year period. Initial diagnoses were established using structured clinical interviews according to DSM-IV diagnostic criteria. Results indicated that the majority of patients meeting DSM-IV diagnostic criteria for GAD were still symptomatic to some degree after 2 years of follow-up. Rates of full and partial recovery from GAD, however, were found to be higher than those reported for previous studies of GAD in psychiatric patients. Diagnostic comorbidity, severity of psychosocial impairment, and gender were found to be significantly associated with achieving full or partial recovery from GAD. Psychiatric treatment was not found to be associated with time to full or partial recovery from GAD symptoms, likely due to a treatment-biasing effect. These results underscore that GAD is a chronic and persistent illness in primary care patients. © 2006 Lippincott Williams & Wilkins, Inc.