Irritant-Associated Vocal Cord Dysfunction : Journal of Occupational and Environmental Medicine

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Irritant-Associated Vocal Cord Dysfunction

Perkner, John J. DO, MSPH; Fennelly, Kevin P. MD, MPH; Balkissoon, Ron MD, MS, DIH; Bartelson, Becki Bucher PhD; Ruttenber, A. James PhD, MD; Wood, Raymond P. II MD; Newman, Lee S. MD, MA

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Journal of Occupational & Environmental Medicine 40(2):p 136-143, February 1998.


Vocal cord dysfunction (VCD) is a poorly understood entity that is often misdiagnosed as asthma. We report eleven cases of VCD in which there was a temporal association between VCD onset and occupational or environmental exposure. We conducted a case-control study to determine if the characteristics of irritant-exposed VCD (IVCD) cases differed from non-exposed VCD controls. Chart review of VCD patients at the authors' institution produced 11 cases that met IVCD case criteria. Thirty-three control VCD subjects were selected by age matching. There were statistical differences between the groups in ethnicity and chest discomfort. There were no statistical differences between the groups for gender, tobacco, smoking habits, symptoms, or pulmonary function parameters. Varied irritant exposures were associated with IVCD. IVCD should be considered in patients presenting with respiratory symptoms occurring after irritant exposures.

© Williams & Wilkins 1998. All Rights Reserved.

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