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Professional Cleaning Activities and Lung Cancer Risk Among Women: Results From the ICARE Study

Atramont, Alice MD; Guida, Florence MD, PhD; Mattei, Francesca PhD; Matrat, Mireille MD; Cenée, Sylvie MS; Sanchez, Marie MS; Carton, Matthieu MD; Menvielle, Gwenn PhD; Marrer, Emilie MD; Neri, Monica PhD; Luce, Danièle PhD; Stücker, Isabelle PhDand the Icare study group

Journal of Occupational and Environmental Medicine: June 2016 - Volume 58 - Issue 6 - p 610–616
doi: 10.1097/JOM.0000000000000722
Original Articles

Objectives: Lung cancer risk associated with occupational cleaning activities has been investigated in the population-based case–control study ICARE.

Methods: Occupational history was collected by standardized interviews. Jobs were first defined according to the International Standard Classification of Occupations (ISCO) codes and then categorized according to activity sectors. Adjusted odds ratios (ORs) were estimated by unconditional logistic regression, separately for women (619 cases and 760 controls) and men (2265 and 2780).

Results: Thirty percent of women and 2.3% of men controls ever held a cleaner or care job. Women who worked as housemaids longer than 7 years showed an OR of 1.76 [95% confidence interval (95% CI) 1.09 to 2.87] with respect to controls. Women employed in domestic service sector for a long time had an OR of 2.06 (95% CI 1.15 to 3.66).

Conclusion: We confirmed and redefined the association of lung cancer with occupational cleaning, which concerns a considerable proportion of women workers.

Université Paris Saclay, Université Paris Sud, UVSQ, CESP, INSERM, Villejuif, France (Drs Atramont, Mattei, Matrat, Ms Cenée, Ms Sanchez, Dr Stücker); Imperial College of London, MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, London, UK (Dr Guida); University Paris Est-Créteil, Faculty of Medicine IFR 10, Créteil (Dr Matrat); Université de Versailles St-Quentin, UMRS 1018 (Dr Carton); INSERM (Dr Menvielle), Sorbonne University, UPMC University of Paris 06, UMR_S 1136, Pierre Louis Institute of Epidemiology and Public Health, Department of social epidemiology, Villejuif (Dr Menvielle); Haut-Rhin Cancer Registry, Centre hospitalier de Mulhouse, ARER 68, Mulhouse Cedex, France (Dr Marrer); Unit of Clinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, Rome, Italy (Dr Neri); INSERM, U1085_IRSET, Pointe-à-Pitre (Dr Luce), and University of Rennes 1, Rennes, France (Dr Luce).

Address correspondence to: Isabelle Stücker, CESP Centre for Research in Epidemiology and Population Health, 16 avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France. (isabelle.stucker@inserm.fr).

The Icare study was supported by Agence Nationale de Sécurité Sanitaire, de l’alimentation, de l’environnement et du travail (ANSES); Fondation de France; Agence Nationale de la Recherche (ANR); Institut National du Cancer (INCA); Fondation pour la Recherche Mèdicale (FRM); Institut national de Veille Sanitaire (InVS); Direction Générale de la Santé (DGS); Fondation ARC pour la Recherche sur le Cancer; Direction Générale du Travail rattachée au Ministère du travail, de l’emploi, de la formation professionnelle et du dialogue social (DGT). This work was funded by la Fondation pour la Recherche Médicale et la Fondation ARC pour la Recherche sur le Cancer.

The ICARE Study Group included Anne-Valérie Guizard; Arlette Danzon; Anne-Sophie Woronoff; Velten Michel; Antoine Buemi; Emilie Marrer; Brigitte Tretarre; Marc Colonna; Patricia Delafosse; Paolo Bercelli; Florence Molinie; Simona Bara; Benedicte Lapotre-Ledoux; Nicole Raverdy; Oumar Gaye; Farida Lamkarkach; Mireille Matrat; Florence Guida; Sylvie Cénée; Matthieu Carton; Diane Cyr; Gwen Menvielle; Sophie Paget-Bailly; Loredana Radoï; Annie Schamus; Alexandra Papadopoulos; Danièle Luce; Isabelle Stücker; Corinne Pilorget; Joëlle Fevotte.

The authors declare that they have no conflict of interest.

Copyright © 2016 by the American College of Occupational and Environmental Medicine