We investigated the association between respiratory health and particulate matter (PM) air pollution in elderly type 2 diabetes mellitus (T2DM) pre-, during, and post-the Chinese Lunar New Year (CLNY) holiday in Shanghai, China.
We conducted repeated measurements of lung function and inflammation biomarker in a cohort consisted of 60 participants with T2DM.
Decreased PM2.5 exposure had an effect on respiratory health by increasing in forced expiratory flow in 1 second (FEV1) and forced vital capacity (FVC). Positive associations between PM exposure and exhaled nitric oxide (eNO) were observed.
Our observations indicated that PM air pollution exposure would exert adverse effect on respiratory health in elderly T2DM population.
Department of Occupational and Environmental Health, School of Public Health, Fudan University (Dr Hao, Mr Wang, Dr Feng, Dr Sun, Dr Chen, Dr Xia); Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (Drs Zhao, Gao), Shanghai; State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Chaoyang District, Beijing (Drs Han, Bai), China; Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, Florida (Dr Zhu).
Address correspondence to: Zhao-lin Xia, PhD, MD, Department of Occupational and Environmental Health, School of Public Health, Fudan University, P.O.288,130 Dong-An Road, Shanghai 200032, China (email@example.com); Ying Gao, PhD, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China (firstname.lastname@example.org).
Dr Hao and Dr Zhao have contributed equally to this work.
Funding: This research was funded by the National Basic Research Program of China (973Program) (2011CB503801; 2015CB553404) and the National Key Technology R&D Program of the 12th National Five-year Development Plan of China (2012BAI05B01).
Authors Xia, Hao, Zhao, Wang, Feng, Sun, Chen, Han, Bai, Zhu, and Gao have no relationships/conditions/circumstances that present potential conflict of interest.
The JOEM editorial board and planners have no financial interest related to this research.