The aim of this study was to compare psychological status, quality of life (QoL), work limitation, and socioeconomic status between patients with occupational asthma (OA) and work-exacerbated asthma (WEA).
The following questionnaires were administered to participants: Beck anxiety and depression (II) inventories, Marks’ Asthma Quality of Life Questionnaire, and Work Limitations Questionnaire. Cross-sectional analyses between OA and WEA subgroups were completed.
There were 77 participants. WEA subjects had a trend to higher anxiety scores (OA = 9.2 ± 8.0, WEA = 12.8 ± 8.3, P = 0.07, Cohen d = 0.4). Depression scores trended higher for those with WEA (OA = 9.6 ± 10.3, WEA = 13.4 ± 13.5, P = 0.2, Cohen d = 0.3). QoL was comparable between groups. WEA subjects had fewer work limitations (N = 50, OA = 25.1 ± 27.3, WEA = 20.6 ± 24.4, P = 0.56, Cohen d = 0.3) and OA subjects were more likely to have reduced income.
In a tertiary clinic, there were some modest differences for specific variables between OA and WEA subjects that may help inform management.
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada (Mr Lipszyc, Drs Silverman, Holness, Tarlo); Toronto Western Hospital, Toronto, Ontario, Canada (Mr Lipszyc, Dr Tarlo); University Health Network, Toronto, Ontario, Canada, Respiratory Division (Dr Tarlo); Department of Occupational and Environmental Health, St. Michael's Hospital, Toronto, Ontario, Canada (Mr Lipszyc, Drs Silverman, Holness, Tarlo); Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (Drs Silverman, Tarlo); Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (Dr Holness); Department of Medicine, University of Toronto, Toronto, Ontario, Canada (Drs Silverman, Holness, Tarlo); Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada (Drs Silverman, Holness, Liss, Tarlo); Montreal Behavioural Medicine Centre, Research Centre, Centre Intégré universitaire de santé et de services sociaux du Nord de l’Ile (CIUSSS-NIM) - Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada (Dr Lavoie); Université du Québec à Montréal (UQAM), Montréal, Quebec, Canada (Dr Lavoie).
Address correspondence to: Susan M. Tarlo, MB, BS, FRCP(C), Toronto Western Hospital EW7-449, 399 Bathurst Street, Toronto, ON M5T 2S8 (firstname.lastname@example.org).
Joshua Lipszyc was supported in part by the Center for Research Expertise in Occupational Disease, funded by the Ontario Ministry of Labour, and from graduate student awards, including the Ontario Graduate Scholarship and Institute of Medical Science Graduate Entry Award, University of Toronto. FS, DLH, GML, and SMT have received grant funding from the Ontario Ministry of Labour. DLH and SMT have also received grant funding for other research from Ontario Workplace Safety and Insurance Board. SMT has also received research funding for other studies from the Ontario Thoracic Society, Canadian Respiratory Research Network, Heart and Stroke Foundation, American Thoracic Society, and has received financial imbursement for clinical review of patients referred from the Ontario Workplace Safety and Insurance Board.