To evaluate the effects of particles and their components on lung function.
A panel study was conducted on 107 primary schoolchildren. The peak expiratory flow rate (PEFR) for each subject was measured three times a day for 40 days continuously. Particulate air concentrations were measured every day. The concentrations of Pb, Ni, Fe, Mn, Cr, As, Cd, and Zn in particles were measured. Linear mixed-effect models were used to estimate the associations between particles, metal elements, and PEFR.
We found that the increase in particles in air was associated with a significant reduction in PEFR. Its effects lasted 2 to 5 days. Pb, Ni, Fe, Mn, and Cr in particles also reduced PEFR. As and Cd increased PEFR. Zn showed inconstant effects on PEFR.
This study suggested that most metal components in particles have negative effects on children's lung function.
From the Department of Occupational and Environmental Health Sciences (Ms Madaniyazi and Mr Pan), School of Public Health, Peking University, People's Republic of China; School of Public Health and Social Work (Drs Guo and Ye), Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; Department of Environmental Health (Dr Kim), National Institute of Environmental Research, Korea; and School of Public Health (Mr Zhang), Baotou Medical College, Baotou, People's Republic of China.
Address correspondence to: Xiaochuan Pan, Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, 38 Xue Yuan Rd, Beijing 100191, People's Republic of China (email@example.com).
This work was supported by the National Institute of Environmental Research, Korea (2007).
Disclosure: The authors declare no conflict of interest.