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Reduction in Diisocyanate and Non-Diisocyanate Sensitizer-Induced Occupational Asthma in Ontario

Buyantseva, Larisa V. MD, MS; Liss, Gary M. MD, MS; Ribeiro, Marcos MD; Manno, Michael MSc; Luce, Carol E. BSc; Tarlo, Susan M. MB, BS

Journal of Occupational and Environmental Medicine: April 2011 - Volume 53 - Issue 4 - p 420–426
doi: 10.1097/JOM.0b013e3182122376
Original Articles

Objective: To investigate relative frequency and features of diisocyanate (ISO) and non-diisocyanate (N-ISO) allowed occupational asthma (OA) claims in Ontario, Canada, during a 5-year period (1998 to 2002).

Methods: Records were abstracted from the Ontario Workplace Safety and Insurance Board using methodology similar to our previous investigation that had identified 30 ISO and 30 N-ISO claims/yr during 1980 to 1993.

Results: There were 99 OA claims: 37 ISO (7.4 claims/yr) and 62 N-ISO (12.4 claims/yr). The ISO group had more males (86% vs 69%, p = 0.01), but there were no other significant differences. The commonest professions were spray painters (41%) and production workers (38%) in the ISO group and production workers (49%) and health care workers (8%) in the N-ISO group.

Conclusions: ISO and N-ISO claims declined from the previous period, especially for ISO, perhaps because of effective surveillance programs.

From the Gage Occupational and Environmental Health Unit (Drs Buyantseva, Liss, and Ribeiro, Tarlo, and Mr Manno), University of Toronto, Toronto, Ontario, Canada; and Ontario Workplace Safety and Insurance Board (Ms Luce), Toronto, Ontario, Canada.

Address correspondence to: Susan M. Tarlo, MB, BS, University Health Network and Gage Occupational and Environmental Health Unit, University of Toronto, Toronto Western Hospital EW7-449, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada; E-mail:

©2011The American College of Occupational and Environmental Medicine