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Quality-of-Life, Psychological, and Cost Outcomes 2 Years After Diagnosis of Occupational Asthma

Miedinger, David MD; Lavoie, Kim L. PhD; L'Archevêque, Jocelyne MT; Ghezzo, Heberto PhD; Zunzunuegui, Maria Victoria PhD; Malo, Jean-Luc MD

Journal of Occupational and Environmental Medicine: March 2011 - Volume 53 - Issue 3 - p 231–238
doi: 10.1097/JOM.0b013e31820d1338
Original Articles: CME Available for this Article at

Objective: To examine the association between clinical and socioeconomic variables and their influence on psychological and cost outcomes in patients with occupational asthma (OA).

Methods: Longitudinal study of 60 subjects who claimed compensation for OA in Quebec. Besides clinical markers of asthma, quality of life (QOL), psychological distress (PD) measures, and an instrument to diagnose mental disorders were used.

Results: The QOL and PD parameters had moderate correlations with clinical markers of OA. Asthma severity, employment, marital status, income, and the length of employment with the employer showed the strongest associations with QOL and PD. More-impaired QOL was associated with higher direct costs for compensation.

Conclusion: Impaired QOL and PD are frequent among subjects with OA receiving compensation and are associated with clinical markers of OA and socioeconomic factors.

Supplemental Digital Content is available in the text.

From the Department of Chest Medicine, Sacré-Coeur Hospital and Université de Montréal (Drs Miedinger, Lavoie, Ghezzo, and Malo and Ms Archevêque), Montreal, Canada; Department of Psychology (Dr Lavoie), University of Quebec in Montreal, Montreal, Quebec, Canada; and Department of Social and Preventive Medicine (Dr Zunzunuegui), Université de Montréal, Montreal, Canada.

Address correspondence to: Jean-Luc Malo, MD, Department of Chest Medicine, Sacré-Coeur Hospital, 5400 Gouin Blvd W, Montreal, QC H4J 1C5, Canada;

David Miedinger is the recipient of a research grant from the Swiss National Science Foundation (PBBSB-120767) and from the Center for Asthma in the Workplace (Canadian Institutes of Health Research). Kim Lavoie is supported by a salary award from the Fonds de la recherche en santé du Québec (FRSQ). Jocelyne L'Archevéque, Heberto Ghezzo, Maria Victoria Zunzunuegui, and Jean-Luc Malo have no financial interest related to this research.

The JOEM Editorial Board and planners have no financial interest related to this research.

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©2011The American College of Occupational and Environmental Medicine