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Impaired Health Status, Daily Functioning, and Work Productivity in Adults With Excessive Sleepiness

Dean, Bonnie PhD; Aguilar, Daniel MPH; Shapiro, Colin PhD; Orr, William C. PhD; Isserman, Joshua A. MS; Calimlim, Brian DrPHc; Rippon, Gregory A. MD

Journal of Occupational and Environmental Medicine: February 2010 - Volume 52 - Issue 2 - p 144-149
doi: 10.1097/JOM.0b013e3181c99505
Original Articles

Objective: This study evaluated the effects of excessive sleepiness (ES) on health status, daily functioning, and work productivity.

Methods: From a survey performed in June to July 2006, people with or without ES in two groups (1758 with obstructive sleep apnea, depression, narcolepsy, multiple sclerosis, or shift work; 1977 without these conditions) were assessed on the Work Productivity and the Activity Impairment Scale, Short Form-12, Medical Outcomes study 6-item Cognitive Function Scale, and the Toronto Hospital Alertness Test.

Results: ES in both groups was associated with highly significant impairments in health status, daily activities, and work productivity for all measures (P < 0.0001), except for absenteeism (P = 0.0400 for group A, P = 0.8360 for group B).

Conclusions: ES may have an incremental negative impact measurable above that of obstructive sleep apnea, multiple sclerosis, narcolepsy, depression, or shift work.

From the Cerner LifeSciences (Dr Dean, Mr Aguilar, Mr Calimlim), Beverly Hills, Calif; Sleep and Alertness Clinic (Dr Shapiro), University Health Network, Toronto, Canada; Lynn Health Science Institute and Oklahoma University Health Sciences Center (Dr Orr), Oklahoma City, Okla; Cephalon, Inc. (Mr Isserman, Dr Rippon), Frazer, Pa; and Department of Emergency Medicine (Mr Isserman), University of Pennsylvania School of Medicine, Philadelphia, Pa.

Address correspondence to: Bonnie B. Dean, PhD, MPH, Cerner LifeSciences, 9100 Wilshire Boulevard, East Tower, Suite 655, Beverly Hills, CA 90212; E-mail:

©2010The American College of Occupational and Environmental Medicine