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The Association Between Asthma Control and Health Care Utilization, Work Productivity Loss and Health-Related Quality of Life

Williams, Setareh A. PhD; Wagner, Samuel PhD; Kannan, Hema MPH; Bolge, Susan C. PhD

Journal of Occupational and Environmental Medicine: July 2009 - Volume 51 - Issue 7 - p 780-785
doi: 10.1097/JOM.0b013e3181abb019
Original Articles

Objective: To determine the association between asthma control and health outcomes.

Methods: Cross-sectional data on asthmatic patients were from the 2006 U.S. National Health and Wellness Survey. Asthma control was determined by the Asthma Control Test. Outcomes assessed included work productivity loss/activity impairment, health-related quality of life, and resource utilization. Effects of asthma control on outcomes were determined with linear and Poisson regression models.

Results: There were 2767 uncontrolled asthmatics and 2912 controlled asthmatics. Adjusting for confounders, controlled asthmatics reported (P < 0.001) higher physical and mental health-related quality of life scores (SF-8); fewer emergency room visits, hospitalization days, and medical provider visits; lower levels of overall work productivity loss and activity impairment.

Conclusion: Results indicate that asthma control is associated with better health outcomes. Management with therapies optimizing asthma control may reduce direct and indirect costs of treatment.

From Health Economics and Outcomes Research (Dr Williams) AstraZeneca LP, Wilmington, Del; and Health Economics and Outcomes Research (Dr Wagner, Dr Kannan, Dr Bolge), Consumer Health Sciences, Princeton, NJ.

Address correspondence to: Hema Kannan, Consumer Health Sciences, 116 Village Blvd., Suite 200, Princeton, NJ 08540; E-mail:

©2009The American College of Occupational and Environmental Medicine