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A Review and Analysis of the Clinical and Cost-Effectiveness Studies of Comprehensive Health Promotion and Disease Management Programs at the Worksite: Update VII 2004–2008

Pelletier, Kenneth R. PhD, MD(hc)

Journal of Occupational and Environmental Medicine: July 2009 - Volume 51 - Issue 7 - p 822-837
doi: 10.1097/JOM.0b013e3181a7de5a
Original Articles

Objective: To conduct the seventh periodic review and analysis of the clinical and cost-effectiveness research conducted in worksite/corporate environments between 2004 and 2008.

Methods: A literature search of US-based research was conducted using a multistage process including MEDLINE, ADI, EDGAR, CARL, Inform, Lexis-Nexis, as well as direct inquiries to key researchers in this area of expertise.

Results: From 2004 to 2008, there were 16 new studies that met the Inclusion/Exclusion criteria. These studies are critiqued and entered into a data table consisting of 13 variables and citations of the 16 new studies.

Conclusions: Clinical and cost-effectiveness research in the worksite/corporate environment continues to evolve although there was only one randomized clinical trial conducted during the most recent interval. There are innovations in pilot studies, quasi-experimental methodologies, and econometric modeling as indicative of future trends.

From the Department of Medicine, University of Arizona School of Medicine, Tucson, Ariz; and Department of Medicine, University of California School of Medicine (UCSF), San Francisco, Calif.

Address correspondence to: Kenneth R. Pelletier, PhD, MD(hc), American Health Association, 1990 North California Blvd., Suite 830, Walnut Creek, CA 94596; E-mail:

©2009The American College of Occupational and Environmental Medicine