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Labor Productivity in Migraine Patients: Primary Care Contribution to Occupational Medicine

Castillo, Jesús MD; Láinez, Miguel J. A. PhD, MD; Domínguez, Manuel PhD, MD; Palacios, Gemma PhD; Díaz, Silvia PhD; Rejas, Javier MD, PhD

Journal of Occupational and Environmental Medicine: August 2008 - Volume 50 - Issue 8 - p 895-903
doi: 10.1097/JOM.0b013e31817e9157
Original Articles

Objective: To estimate the impact of migraine on labor productivity and health resources utilization in an active population attending Primary Care settings in Spain.

Methods: An observational, cross-sectional, and multicenter study was designed. Productivity, loss workdays equivalents and previous 3-months health resources utilization were calculated.

Results: Four thousand four hundred twenty six patients were evaluated. The migraine group showed the lowest productivity, highest loss workdays equivalents and health resources utilization compared with non-migraine headaches and subjects without headaches (P < 0.05 in all cases). Within the migraine group, lower productivity values were observed in female patients compared to male (64.04 vs 59.69; P < 0.05), while emergency room visits were more frequent for male patients (0.71 vs 076; P < 0.05).

Conclusions: Subjects with migraine showed higher impact on health resources utilization and productivity when evaluated at Primary care level.

From the Primary Care Health Center of Camargo (Dr Castillo), Muriedas, Cantabria; Department of Neurology (Dr Láinez), University Hospital of Valencia, Valencia; Department of Neurology (Dr Domínguez), Hospital Central de la Defensa, Madrid; CNS Therapeutic Area (Dr Palacios), Medical Unit, Pfizer SA, Alcobendas (Madrid); Health Outcomes Research (Dr Díaz), Euroclin Institute, Madrid, Spain; and Health Outcomes Research (Dr Rejas), Medical Unit, Pfizer SA, Madrid, Spain.

CME Available for this Article at

Javier Rejas and Gemma Palacios are employed by Pfizer Spain, which also provided funding for the research discussed in this article.

Address correspondence to: Dr Jesús Castillo, Primary Care Health Center “José Barros,” Avda, Bilbao s/n, 39600, Muriedas (Cantabria), Spain; E-mail:

Copyright © 2008 by the American College of Occupational and Environmental Medicine