The objective of this study was to determine if there is an additional risk of developing Hodgkin lymphoma, multiple myeloma, or soft tissue sarcoma as a consequence of exposure to a combination of phenoxyherbicides, rubber gloves, DEET (N, N-diethyl-m-toluamide), and sunlight compared with each of the individual chemicals.
This was a population-based study of men with specific cancers and age, province-matched control subjects.
No additional risk from these combinations of exposures of developing these three types of tumor was found in contrast to non-Hodgkin lymphoma.
The mechanisms by which phenoxyherbicides contribute to the risk of multiple myeloma and non-Hodgkin lymphoma may be different.
From the Institute of Agricultural Rural and Environmental Health (Dr Pahwa, Dr McDuffie, Dr Dosman), University of Saskatchewan, Saskatchewan, Canada; Samuel Lunenfeld Research Institute (Dr McLaughlin), University of Toronto, Toronto, Canada; Cancer Control Research (Dr Spinelli), British Columbia Cancer Agency, British Columbia, Canada; retired, formerly Saskatchewan Cancer Agency (Ms Robson), Saskatchewan, Canada; and retired, formerly Division of Epidemiology, Prevention and Screening (Dr Fincham), Alberta Cancer Agency, Alberta, Canada.
Address correspondence to: Helen H. McDuffie, PhD, Institute of Agricultural Rural and Environmental Health, 103 Hospital Drive, P.O. Box 120, R.U.H., Saskatoon, Saskatchewan S7N 0W8, Canada; E-mail: email@example.com.