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Biological Monitoring of Exposures to Aluminium, Gallium, Indium, Arsenic, and Antimony in Optoelectronic Industry Workers

Liao, Y -H. MS; Yu, H -S. MD; Ho, C -K. MD; Wu, M -T. MD; Yang, C -Y. MD; Chen, J -R. MD; Chang, C -C. MD

Journal of Occupational and Environmental Medicine: September 2004 - Volume 46 - Issue 9 - p 931-936
doi: 10.1097/01.jom.0000137718.93558.b8
Original Articles

The main objective of this study was to investigate aluminum, gallium, indium, arsenic, and antimony exposures on blood and urine levels in the optoelectronic workers. One hundred seventy subjects were enrolled in this cohort study. Whole blood and urine levels were determined by inductively coupled plasma-mass spectrometry. Blood indium and urine gallium and arsenic levels in the 103 workers were significantly higher than that in 67 controls during the follow-up period. In regression models, the significant risk factors of exposure were job title, preventive equipment, Quetelet’s index, sex, and education level. The findings of this study suggest that gallium, indium, and arsenic exposure levels may affect their respective levels in blood and urine. The use of clean, preventive equipment is recommended when prioritizing the administration of safety and hygiene in optoelectronics industries.

From the Department of Public Health, Kaohsiung Medical University, Kaohsiung (Mr Liao, Dr Chang, Dr Yang); Department of Dermatology, National Taiwan University College of Medicine, Taipei (Dr Yu); Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung (Dr Ho); Graduate Institute of Occupational Safety and Health, Kaohsiung Medical University, Kaohsiung (Dr Wu); and Department of Health, Kaohsiung Municipal Government, Kaohsiung (Dr Chen), Taiwan.

Supported by National Science Council grant No. NSC 87–2621-B-037–002-Z.

Address correspondence to: Yen-Hsiung Liao, MS, Instructor, School of Public Health, Kaohsiung Medical University, Kaohsiung Taiwan. 100, Shih-Chuan 1st Road, Kaohsiung, Taiwan; E-mail address:

©2004The American College of Occupational and Environmental Medicine