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Illness Experience Before and After an Initiative to Identify, Treat, and Prevent Helicobacter pylori-related Diseases in the Workplace

Ott, M. Gerald PhD; Zober, Andreas MD, PhD; Messerer, Peter MS; Riemann, Jürgen F. MD; Schilling, Dieter MD

Journal of Occupational and Environmental Medicine: March 2004 - Volume 46 - Issue 3 - p 227-233
doi: 10.1097/01.jom.0000116817.54229.e8

Objective outcome measures are needed to confirm the merits of large-scale health initiatives in the workplace. We used aggregate medical claims data to evaluate the illness experience of 5160 employees during the 2 years after versus the 2 years before an intervention intended to identify, treat, and prevent Helicobacter pylori-related illnesses. Across all participants, a 2.1-fold reduction (95% confidence interval 1.4–3.1) in ulcer-related illness episodes and a marginal 1.1-fold reduction (95% confidence interval 0.9–1.4) in episodes due to other stomach and duodenal diseases were achieved. Improvement in claims experience was most notable among 250 employees with ulcer findings on the screening examination. This H. pylori health initiative appears to have contributed to a cost-effective reduction in subsequent illness episodes due to ulcer and possibly due to other stomach and duodenal disease.

Occupational Medical and Health Protection Department, BASF Aktiengesellschaft, Ludwigshafen, Germany (Dr Zober, Mr Messerer); Medical Clinic C of the Municipal Clinic of Ludwigshafen GmbH, Ludwigshafen, Germany (Dr Riemann, Dr Schilling); and Corporate Medical Department, BASF Corporation, Mt. Olive, New Jersey (Dr Ott).

Address correspondence to: Andreas Zober, MD, PhD, Medical Department, BASF, Ludwigshafen, D-67056 Germany; E-mail address:

Andreas Zober has no commercial interest related to this article.

©2004The American College of Occupational and Environmental Medicine