Review ArticleGlycemia Management in Neurocritical Care Patients: A ReviewBilotta, Federico MD, PhD; Giovannini, Federico MD; Caramia, Remo MD; Rosa, Giovanni MDAuthor Information Department of Anesthesiology, Intensive Care and Pain Medicine, “Sapienza,” University of Rome, Rome, Italy Disclosure: The authors have reported no conflicts of interest. This work was done in the Department of Neuroanaesthesia, University of Rome “La Sapienza,” Rome, Italy. Reprints: Federico Bilotta, MD, PhD, Department of Anesthesiology, Critical Care and Pain Medicine, Viale Somalia 81, Rome 00199, Italy (e-mail: [email protected]). Received for publication April 24, 2008; accepted September 25, 2008 Journal of Neurosurgical Anesthesiology: January 2009 - Volume 21 - Issue 1 - p 2-9 doi: 10.1097/ANA.0b013e31818f8a5c Buy Metrics Abstract Intensive research investigating the relation between the management of glycemia and outcome in patients receiving neurocritical care has underlined the possible benefits and adverse events related to glucose control. Here, we review experimental and clinical studies investigating the effects of hypoglycemia and hyperglycemia on the brain that advance current knowledge on managing glycemia in patients receiving neurocritical care. © 2009 Lippincott Williams & Wilkins, Inc.