Special Interest ArticlesFrom Disease to Health: Physical Therapy Health Promotion Practices for Secondary Prevention in Adult and Pediatric Neurologic PopulationsQuinn, Lori PT, EdD; Morgan, Don PhDAuthor Information Department of Biobehavioral Sciences, Teachers College, Columbia University, New York (L.Q.); and Department of Health and Human Performance, Middle Tennessee State University, Murfreesboro (D.M.). Correspondence: Lori Quinn, PT, EdD, Associate Professor, Department of Biobehavioral Sciences, 525 West 120th St, Box 199, Teachers College, Columbia University, New York, NY 10027 ([email protected]). The authors declare no conflict of interest. Journal of Neurologic Physical Therapy: July 2017 - Volume 41 - Issue - p S46-S54 doi: 10.1097/NPT.0000000000000166 Buy Metrics Abstract Background and Purpose: Over the last decade there has been a substantial increase in efforts to better understand how targeted physical activity and exercise interventions can be used to minimize secondary consequences arising from neurological damage in both adult and pediatric populations. This article offers an overview of contemporary research that addresses mediators of functional and neuroplastic adaptations associated with physical activity and exercise. We emphasize the important role that physical therapists can play to increase participation and improve well-being in adults and children with neurological disorders. We further highlight potential strategies to foster translation of evidence-based findings for use by clinicians and consumers. Summary of Key Points: Engagement in physical activity can serve as a powerful promoter of health and well-being in adults and youth with neurologic disease, and has the potential to alter the course of disease processes. Physical therapists can play a key role in promoting fitness and wellness by encouraging active living, providing early diagnosis of disease and prescribing targeted activity interventions to improve fitness and participation, and helping individuals overcome personal and environmental barriers to an active lifestyle. Recommendations for Clinical Practice: Physical therapists must adopt a model of rehabilitation that emphasizes secondary prevention in adults and youth with neurologic diseases. Physical therapists have a unique role in developing forward-thinking approaches in using innovative health and wellness strategies to promote positive changes in activity and exercise behaviors. © 2017 Academy of Neurologic Physical Therapy, APTA.