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Implementation of Intranasal Midazolam for Prolonged Seizures in a Child Neurology Practice

Crawford, Daniel

Journal of Neuroscience Nursing: December 2016 - Volume 48 - Issue 6 - p 315–321
doi: 10.1097/JNN.0000000000000234

ABSTRACT Currently, evidence supports the use of intranasal midazolam as an effective, and in many cases, preferable treatment option for prolonged seizures in children. Despite this knowledge, intranasal midazolam is not routinely found as a standard of care. The goal of this project was to implement the use of intranasal midazolam as a rescue medication for prolonged seizures within a child neurology practice and, in doing so, create a model for implementation that would be replicable for other practice sites. This project focused on the development of a process to make intranasal midazolam available as a treatment option and then the creation of an educational intervention for providers within a child neurology practice. Provider surveys analyzed provider attitudes toward intranasal midazolam and its frequency of use. Because of this project, a dramatic increase in the prescribing of intranasal midazolam was observed within a child neurology practice.

Questions or comments about this article may be directed to Daniel Crawford, DNP RN CPNP, at He is a Clinical Assistant Professor at Arizona State University in the College of Nursing & Health Innovation and a Pediatric Nurse Practitioner in Child Neurology at Banner Children’s Specialists in Mesa, Arizona.

The author declares no conflicts of interest.

© 2016 American Association of Neuroscience Nurses