Journal of Neuro-Ophthalmology

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June 2023 - Volume 43 - Issue 2

  • Laura J. Balcer, MD, MSCE
  • 1070-8022
  • 1536-5166
  • 4 issues / year
  • 89/267 in Clinical Neurology; 13/61 in Ophthalmology
  • 4.415

Current Issue Highlights

Epidemiology Meets Neuro-Ophthalmology

Deep Learning System Outperforms Clinicians in Identifying Optic Disc Abnormalities

Vasseneix, Caroline; Nusinovici, Simon; Xu, Xinxing; More

Journal of Neuro-Ophthalmology. 43(2):159-167, June 2023.


The JNO, in conjunction with NANOS, has a new program of presenting engaging and challenging cases aimed at residents in ophthalmology and neurology (as well as medical students). The project is called Unknown Patients For Residents in Ophthalmology and Neurology Training, which we refer to as UPFRONT Cases. These cases are free for all to access and are presented as unknowns, with the reader having to work through the differential diagnosis, evaluation, and therapy of these patients. These cases are carefully selected by a committee from cases proposed by the NANOS membership. Our goal is to engage the reader, as they are not everyday cases, and to demonstrate the role of a neuro-ophthalmologist in the evaluation and management of these patients. It is difficult to get a clinical neuro-ophthalmology rotation, especially in this COVID era, and so these cases are also intended to help expose neurology and ophthalmology residents to what a neuro-ophthalmologist sees and does. For optimal performance, please view the cases in presentation format. 

Case 1: "Double Vision and Headache" by Larry Frohman​

Case 2: "Vertical Nystagmus" by Sugi Pann​​​eerselvam, Subahari Raviskanthan, and Andrew G. Lee ​

Case 3: "Double Vision and Headache II" by Larry Frohman and Christopher Seery​​

Case 4: "Subacute Bilateral Vision Loss" by Vladislav Bekerman, Roger Turbin, and Larry Frohman

Case 5: "Papilledema in a Patient Being Treated for Multiple Sclerosis" by Larry Frohman, Roger Turbin, Peter Wawrzusin, Gaurav Srivastava, and Nicole Sakla​

Case 6: "An Older Patient with Difficulty Reading​" by Victoria S. Pelak 

Case 7: "Post-Operative Vision Loss" by Amir Ali, Subahari Raviskanthan, Ardalan Sharifi, Andrew G. Lee​

Case 8: "Acute Onset of Diplopia in an Uncontrolled Diabetic" by Aditya Gill, Roger Turbin, Larry Frohman

Case 9: "Intractable Headache and Vomiting in a Pediatric Patient" by Khelly Shah, Larry Frohman​

Case 10: "Bilateral Vision Loss in a Young Patient" by Jorge Cardenas-Belaunzaran, Octavio Turcio Aceves, Vianney Cortes Gonzalez​

Case 11: "Fuzzy Side" by Mehdi Tavakoli, Danielle R. Isen, Aparna Singhal, James R. Hackney​​

Case 12: "Recurrent Branch Retinal Artery Occlusions" by Francisco Sanchez, Tariq Bhatti, John J. Chen

Case 13: "Acute, Bilateral Visual Loss in a Pediatric Patient" by Elizabeth H. Roll, Larry P. Frohman, Roger E. Turbin​

Case 14: "Ophthalmoplegia in Patient with Papilledema" by Larry Frohman, Eric S. Hwang​

Case 15: "Unexplained Bilateral Optic Atrophy for Decades"​ by Chaow Charoenkilkajorn, Junsang Cho, Andrew G. Lee​

Case 16: "Abduction Deficit" by Mehdi Tavakoi, Natalie DeBolske, Robert C Foster ​

Case 17: "Vision Loss in a Cancer Patient" by Denis Huang, MD, Neesurg S. Mehta, MD, Kit W. Tam, MD, Kareem Moussa, MD, Yin Allison Liu, MD, PhD​

Case 18: "A Diagnostic Conundrum of Bilateral Optic Disc Edema" by Praveen Jeyaseelan, MD, Andrew R. Casey, MD

Case 19: "Headache, Confusion, and Hearing Loss" by Abigail Jebaraj MD, Sam Wilkinson MD, Jacob Nydegger, and Meagen Seay DO​

Case 20: "Movie-Like Palinopsia" by Heather M. McDonald, MD, Lulu L.C.D. Bursztyn, MD, FRCPC, J. Alexander Fraser, MD, FRCPC​

Case 21: "Eye Swelling and Decreased Vision in a Patient with Autism" by Jia Xu, MD, Yanjia Jason Zhang, MD, Efren Gonzalez, MD, Thomas Hs. Dohlman, MD, Eric D. Gaier MD, PhD​

Case 22: "Blurred Disc Margins" by John O.T. Britton, Patrick Yu-Wai-Man, Benson S. Chen​

Case 23: "Nystagmus and Dysphagia" by Christian Leal, MD, Andrew Melson, MD​