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Vision Loss and Symmetric Basal Ganglia Lesions in Leber Hereditary Optic Neuropathy

Mercuri, Matthew A. MD; White, Halina MD; Oliveira, Cristiano MD

doi: 10.1097/WNO.0000000000000524
Clinical Observation

Abstract: A 30-year-old woman with progressive vision loss was found to have asymptomatic, bilateral, and symmetric basal ganglia lesions on MRI and was later diagnosed with Leber hereditary optic neuropathy (LHON). The rare occurrence of basal ganglia changes on MRI in patients with LHON is discussed.

Departments of Neurology (MAM, HW) and Ophthalmology (CO), Weill Cornell Medical College, New York, New York.

Address correspondence to Cristiano Oliveira, MD, 1305 York Avenue 11th Floor, New York, NY 10021; E-mail:

Supported by a Research to Prevent Blindness (RPB) unrestricted grant to the Weill Cornell Department of Ophthalmology.

The authors report no conflicts of interest.

© 2017 by North American Neuro-Ophthalmology Society