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The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography

Malmqvist, Lasse, MD; Bursztyn, Lulu, Msc, MD; Costello, Fiona, MD, PhD; Digre, Kathleen, MD; Fraser, J. Alexander, MD; Fraser, Clare, MMed; Katz, Bradley, MD, PhD; Lawlor, Mitchell, FRANZCO, PhD; Petzold, Axel, MD, PhD; Sibony, Patrick, MD; Warner, Judith, MD; Wegener, Marianne, MD; Wong, Sui, MD; Hamann, Steffen, MD, PhD

doi: 10.1097/WNO.0000000000000585
Original Contribution

Background: Making an accurate diagnosis of optic disc drusen (ODD) is important as part of the work-up for possible life-threatening optic disc edema. It also is important to follow the slowly progressive visual field defects many patients with ODD experience. The introduction of enhanced depth imaging optical coherence tomography (EDI-OCT) has improved the visualization of more deeply buried ODD. There is, however, no consensus regarding the diagnosis of ODD using OCT. The purpose of this study was to develop a consensus recommendation for diagnosing ODD using OCT.

Methods: The members of the Optic Disc Drusen Studies (ODDS) Consortium are either fellowship trained neuro-ophthalmologists with an interest in ODD, or researchers with an interest in ODD. Four standardization steps were performed by the consortium members with a focus on both image acquisition and diagnosis of ODD.

Results: Based on prior knowledge and experiences from the standardization steps, the ODDS Consortium reached a consensus regarding OCT acquisition and diagnosis of ODD. The recommendations from the ODDS Consortium include scanning protocol, data selection, data analysis, and nomenclature.

Conclusions: The ODDS Consortium recommendations are important in the process of establishing a reliable and consistent diagnosis of ODD using OCT for both clinicians and researchers.

Department of Ophthalmology (LM, MW, SH), Rigshospitalet, University of Copenhagen, Denmark; Department of Ophthalmology (LB, AF), Western University, London, Ontario, Canada; Departments of Clinical Neurosciences and Surgery (FC), University of Calgary, Calgary, Canada; John A. Moran Eye Centre (KD, BK, JW), University of Utah, Salt Lake City, Utah; Department of Clinical Neurological Sciences (AF), Western University, London, Ontario, Canada; Save Sight Institute (CF), University of Sydney, New South Wales, Australia; Sydney Eye Hospital (ML), Sydney, New South Wales, Australia; Department of Neurology (AP, SW), Moorfields Eye Hospital, London, United Kingdom; Neuro-ophthalmology Expertise Centre (AP, SW), VUmc, Amsterdam, the Netherlands; and Department of Ophthalmology (PS), State University of New York at Stony Brook, Stony Brook, New York.

Address correspondence to Lasse Malmqvist, MD, Department of Ophthalmology, Rigshospitalet, Nordre Ringvej 57, 2600 Glostrup, Denmark; E-mail:

The authors report no conflicts of interest.

© 2018 by North American Neuro-Ophthalmology Society