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Focal Capillary Dropout Associated With Optic Disc Drusen Using Optical Coherence Tomographic Angiography

Gaier, Eric D. MD, PhD; Rizzo, Joseph F. III MD; Miller, John B. MD; Cestari, Dean M. MD

doi: 10.1097/WNO.0000000000000502
Clinical Observation

Abstract: Optic disc drusen may be a cause of visual field defects and visual loss. The mechanism by which this occurs is unclear. We report a patient who developed decreased vision in the right eye and was found to have a heavy burden of superficial optic disc drusen. Optical coherence tomography (OCT) confirmed focal retinal nerve fiber layer thinning that corresponded with the distribution of drusen. OCT angiography, with superficial laminar segmentation, showed focal capillary attenuation overlying the most prominent drusen. These findings demonstrate alterations in the superficial retinal capillary network associated with optic disc drusen.

Neuro-Ophthalmology (EDG, JFR, DMC) and Retina (JBM), Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Address correspondence to Dean M. Cestari, MD, Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114; E-mail:

The authors report no conflicts of interest.

© 2017 by North American Neuro-Ophthalmology Society