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Papilledema Due to a Permanent Catheter for Renal Dialysis and an Arteriovenous Fistula: A “Two Hit” Hypothesis

Simon, Melissa A. MD; Duffis, Ennis J. MD; Curi, Michael A. MD; Turbin, Roger E. MD; Prestigiacomo, Charles J. MD; Frohman, Larry P. MD

Journal of Neuro-Ophthalmology: March 2014 - Volume 34 - Issue 1 - p 29–33
doi: 10.1097/WNO.0000000000000063
Original Contribution

Abstract: Elevated intracranial pressure in patients with chronic renal failure has several potential causes. Its rare occurrence secondary to the hemodynamic effects of hemodialysis is described and the findings support a multifactorial etiology (“two hits”).

Departments of Ophthalmology and Visual Science (MAS, RET, LPF), Neurosurgery (EJD), Vascular Surgery (MAC), Neurology and Neurosciences (LPF), Rutgers-New Jersey Medical School, Newark, New Jersey.

Address correspondence to Melissa A. Simon, MD, 90 Bergen Street, Suite 6100, Newark, NJ 07103; E-mail:

The authors report no conflicts of interest.

© 2014 by North American Neuro-Ophthalmology Society