ArticlesThe Effect of Buzzy Application on Pain Level During Vaccine Injection in InfantsŞıktaş, Özge BSc; Uysal, Gülzade PhD, RN Author Information Bakırköy No. 9 Family Health Center, Neighbourhood of Basınköy, Bakırköy, Turkey (Ms Şıktaş); and Faculty of Health Sciences, Sakarya University of Applied Sciences, Sakarya, Turkey (Dr Uysal). Correspondence: Gülzade Uysal, PhD, RN, Faculty of Health Sciences, Sakarya University of Applied Sciences, Sakarya, Turkey ([email protected]). This research was carried out as a master degree thesis at the Istanbul Okan University Institute of Health Sciences, Nursing Department, and presented at the oral session of the 18th National Child Nursing Congress in Cyprus between October 30 and November 3, 2019. We would like to express our thanks to our colleagues at Bakirkoy No. 9 Family Health Center for their great assistance and help. We also share our appreciation for the infants and their parents who volunteered to take part in the research. The authors declare no conflicts of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jncqjournal.com). Accepted for publication: June 28, 2022 Early Access: September 5, 2022 Journal of Nursing Care Quality: January/March 2023 - Volume 38 - Issue 1 - p E9-E15 doi: 10.1097/NCQ.0000000000000656 Buy SDC Metrics Abstract Background: Nonpharmacological interventions are needed to reduce pain during vaccine administration in infants. Purpose: To determine the effect of the Buzzy device, which is a combination of cold and vibration, on pain during measles-mumps-rubella (MMR) vaccine administration in 12-month-old infants. Methods: A prospective randomized controlled experimental research design was used. Results: A total of 60 infants were included in the study. During and after vaccine injection, pain scores of infants who had the Buzzy device were significantly lower than those of infants in the control group (P = .001). Conclusions: Buzzy application may be an effective method in reducing pain during MMR vaccine administration. Use of the device is recommended for infants receiving vaccinations. © 2022 Wolters Kluwer Health, Inc. All rights reserved.