ArticlesImpact of Interruptions, Distractions, and Cognitive Load on Procedure Failures and Medication Administration ErrorsThomas, Lily PhD, RN, FAAN; Donohue-Porter, Patricia PhD, RN; Stein Fishbein, Joanna MPHAuthor Information Northwell Health, New Hyde Park, New York (Dr Thomas); Adelphi University College of Nursing and Public Health, Garden City, New York (Dr Donohue-Porter); and Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York (Ms Fishbein). Correspondence: Lily Thomas, PhD, RN, FAAN, Northwell Health, 400 Lakeville Road, Suite 170, North New Hyde Park, NY 11042 (firstname.lastname@example.org). The authors thank Dr Kathleen Stevens and ISRN Network Study Research Collaborative on Medication Errors, Maureen White, Dr Jane White, Dr Martin L. Lesser, and James F. McKenna for their support from design to completion of the study. The authors also acknowledge the contributions of the site PIs who were members of the ISRN Research Collaborative of the national network study on medication errors.Organizations of Drs Thomas and Donohue- Porter received a onetime consultation fee from ISRN, The University of Texas Health Science Center at San Antonio. Drs Thomas and Donohue-Porter received an honorarium for presenting at the ISRN Summit.Partial financial support was provided by National Institutes of Health Grand Opportunities ARRA 1RC2NR011946-01, 3RC2NR011946-01S1, 3RC2NR011946-01S2, Stevens, PI.The authors declare no conflict of interest.Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jncqjournal.com).Accepted for publication: February 1, 2017Published ahead of print: April 26, 2017 Journal of Nursing Care Quality: October/December 2017 - Volume 32 - Issue 4 - p 309-317 doi: 10.1097/NCQ.0000000000000256 Buy SDC Metrics Abstract Medication administration errors are difficult to intercept since they occur at the end of the process. The study describes interruptions, distractions, and cognitive load experienced by registered nurses during medication administration and explores their impact on procedure failures and medication administration errors. The focus of this study was unique as it investigated how known individual and environmental factors interacted and culminated in errors. © 2017 Wolters Kluwer Health, Inc. All rights reserved.