The Bethesda System for gynecologic cytopathology has standardized reporting terminology over the past quarter of a century. In doing so, it has allowed for improved communication among practitioners around the world, facilitated large research projects and clinical trials, and has provided the basis from which uniformly accepted risk-based management strategies have been developed. Over time, changes in terminology and the underlying science require revisions, and the third edition of the Bethesda “Atlas” is the result of a yearlong effort to provide such an update. New material was developed and proposed via an Internet bulletin board, allowing for wide commentary that was compiled and incorporated. New images were collected, which comprised many new examples of equivocal presentations and mimics. New background material on the scientific basis supporting the terminology categories, the most current management algorithms, and comprehensive references were included. The effort completely refurbishes this standard reference that forms an inexpensive and, therefore, widely available resource for the world’s cytology community.
1Department of Pathology, Northwestern University, Feinberg School of Medicine, Northwestern Medicine, Chicago, IL; and 2Departments of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Correspondence to: Ritu Nayar, MD, Northwestern University Feinberg School of Medicine, Chicago, IL 60611. E-mail: firstname.lastname@example.org
Funding Support: None for The Bethesda 2014 Atlas Update Project.
Conflict of Interest Disclosures: Dr Nayar was an immediate past president of American Society of Cytopathology in 2013–2014. Dr Wilbur was a past president of American Society of Cytopathology in 2002–2003.
This article is jointly published in Journal of the American Society of Cytopathology, Cancer Cytopathology, Journal of Lower Genital Tract Disease, and Acta Cytologica by the American Society of Cytopathology, the American Cancer Society, the American Society for Colposcopy and Cervical Pathology, and the International Academy of Cytology.
© 2015 American Cancer Society, Inc., American Society of Cytopathology, American Society for Colposcopy and Cervical Pathology, and International Academy of Cytology.
Published online Month 00, 2015, in Wiley Online Library (wileyonlinelibrary.com)
DOI: 10.1002/cncy.21521, wileyonlinelibrary.com