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Massive Localized Lymphedema of the Vulva: Report of a Case and Review of the Literature

Heller, Debra S. MD1,2; Fitzhugh, Valerie A. MD1; Cracchiolo, Bernadette MD, MPH2; Barrett, Theodore Jr. MD2; Suidan, Rudy S. MD2

Journal of Lower Genital Tract Disease: April 2014 - Volume 18 - Issue 2 - p E46–E49
doi: 10.1097/LGT.0b013e31829cf432
Case Reports

Background Massive localized lymphedema (MLL) is a recently described entity associated with obesity, most often on the thighs. It rarely occurs on the vulva, and it may pose diagnostic difficulty for both clinician and pathologist in this setting.

Case An obese 55-year-old woman underwent excision of bilateral polypoid vulvar masses. Histology confirmed the diagnosis of MLL.

Conclusions Although MLL is not common on the vulva, with the increasing incidence of obesity in the population, more cases can be anticipated, and an awareness of this lesion is important.

Massive localized lymphedema, a recently described entity associated with obesity, can occur on the vulva.

Departments of 1Pathology and Laboratory Medicine and 2Obstetrics, Gynecology, and Women’s Health, Rutgers New Jersey Medical School, Newark, NJ

Correspondence to: Debra S. Heller, MD, Department of Pathology, UH/E158, UMDNJ-New Jersey Medical School, 185 S Orange Ave, Newark, NJ 07103. E-mail:

The author has declared that there are no conflicts of interest.

Copyright © 2014 by the American Society for Colposcopy and Cervical Pathology