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Pseudoangiomatous Stromal Hyperplasia of the Vulva Presenting as a Polypoid Vulvar Lesion: A Lesion Associated With Anogenital Mammary-Like Tissue—Report of a Case and Review of the Literature

Heller, Debra S. MD1,2; Aisner, Seena C. MD1; Fitzhugh, Valerie A. MD1; Katava, Gordana DO1; Barrett, Theodore MD2

Journal of Lower Genital Tract Disease: October 2013 - Volume 17 - Issue 4 - p e5–e7
doi: 10.1097/LGT.0b013e31827a8aa2
Case Reports

Objective The study aimed to report the case of a patient with a polypoid vulvar lesion clinically thought to be an aggressive angiomyxoma.

Materials and Methods On examination, a 4.0 × 2.0 × 1.5-cm polypoid lesion was seen on the right labium majus.

Results Histopathological findings of the excised mass were consistent with pseudoangiomatous stromal hyperplasia of the vulva

Conclusions Pseudoangiomatous stromal hyperplasia is a lesion of breast tissue but can occur in anogenital mammary-like glands. It must be distinguished from low-grade angiosarcoma.

A case of pseudoangiomatous stromal hyperplasia of the vulva is presented, and the entity is discussed.

Departments of 1Pathology and Laboratory Medicine, and 2Obstetrics, Gynecology, and Women’s Health, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ

Reprint requests to: Debra S. Heller, MD, Department of Pathology-UH E158 UMDNJ-NJMS 185 South Orange Ave, Newark, NJ 07103. E-mail:

The authors have declared that there are no conflicts of interest.

Copyright © 2013 by the American Society for Colposcopy and Cervical Pathology