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Prevalence of Recurrent Vulvovaginal Candidiasis in 5 European Countries and the United States: Results From an Internet Panel Survey

Foxman, Betsy PhD1; Muraglia, Ryan BS1; Dietz, Jean-Paul PhD2; Sobel, Jack D. MD3; Wagner, Julian PhD4

Journal of Lower Genital Tract Disease: July 2013 - Volume 17 - Issue 3 - p 340–345
doi: 10.1097/LGT.0b013e318273e8cf
Basic Science

Objective This study aimed to estimate prevalence of vulvovaginal candidiasis (VVC) and recurring VVC (RVVC).

Materials and Methods An online omnibus survey was administered to 6,010 women aged 16 and older in 6 countries.

Results We analyzed surveys from 6,000 women. Depending on the country, between 29% and 49% of participating women reported having a health care provider–diagnosed vaginal yeast infection during their lifetime. More than one fifth of women reporting one vaginal yeast infection also reported a 12-month period with 4 or more infections (RVVC) (overall 9%). The cumulative probability of RVVC after an initial vaginal yeast infection was very high. By age 25 years, the probability was 10% for women having had 1 initial yeast infection. By age 50 years, it was 25%.

Conclusions The overall rates of VVC and RVVC were high and consistent with previous findings. Results were consistent across countries with the exception of France, which had a lower rate of VVC. This may reflect differences in risk behavior, response to infection, or sampling biases. Recurring VVC is a significant health problem in western countries, and the probability that VVC will progress to RVVC is high.

Recurring VVC is a significant health problem in western countries, and the probability that VVC will progress to RVVC is high.

1Department of Epidemiology, University of Michigan, Ann Arbor, MI; 2HMAccess, Health and Market Access Strategies S.A.S., France; 3Division of Infectious Diseases, Department of Internal Medicine, Wayne State University, Detroit, MI; and 4Pevion Biotech AG, Bern, Switzerland

Reprint requests to: Betsy Foxman, PhD, Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109-2029. E-mail: bfoxman@umich.edu

The authors have declared they have no conflicts of interest.

This work was supported by Pevion Biotech AG, Switzerland.

Copyright © 2013 by the American Society for Colposcopy and Cervical Pathology