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Vaginal Blue Nevus: Report of a Case and Review of the Literature

Fitzhugh, Valerie A. MD; Houck, Karen MD; Heller, Debra S. MD

Journal of Lower Genital Tract Disease: October 2011 - Volume 15 - Issue 4 - p 325-327
doi: 10.1097/LGT.0b013e318213f3b8
Case Reports

Objective: Blue nevi are extremely rare in the vaginal canal and are suspicious for melanoma, especially when multiple lesions are present. We describe a woman with multiple blue nevi of the vagina.

Design: We describe 1 case of multiple blue nevi of the vagina.

Results: A 37-year-old woman, status after therapy for serous carcinoma of the ovary, presented with multiple blue to black macular lesions present throughout the vagina. Two of the lesions were examined by biopsy and demonstrated dendritic melanocytes. The patient has been closely followed, and the lesions remain unchanged.

Conclusions: Multiple vaginal blue nevi are an important differential diagnostic consideration for melanoma of the vagina. These lesions, however, are benign and require only clinical follow-up. Excision is unnecessary.

Vaginal blue nevi are rare and are an important differential diagnosis for vaginal melanoma.

University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ

Correspondence to: Valerie A. Fitzhugh, MD, Department of Pathology and Laboratory Medicine, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, 185 S Orange Ave, Newark, NJ 07103. E-mail:

The authors have no funding to disclose.

©2011The American Society for Colposcopy and Cervical Pathology