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Giant Condyloma Versus Verrucous Carcinoma: A Case Report

Bambao, Clarissa MD1; Nofech-Mozes, Sharon MD2; Shier, Michael MD1

Journal of Lower Genital Tract Disease: July 2010 - Volume 14 - Issue 3 - p 230-233
doi: 10.1097/LGT.0b013e3181c945ed
Case Reports

Giant condyloma acuminatum is a large, slow-growing, exophytic, cauliflower-like tumor of the external genitalia. It is a histologically benign lesion, largely associated with human papillomavirus infection but with a high recurrence rate. The main differential diagnosis includes verrucous carcinoma. Differentiation between these 2 types of tumors is important with respect to treatment and prognosis. We present a case report of a 26-year-old woman with giant condyloma acuminata of the vulva and discuss the histological features and treatment modalities of this condition.

Précis: A case report of giant condyloma acuminata in a 26-year-old woman and a discussion of its differential diagnosis and histological features.

Departments of 1Obstetrics and Gynaecology and 2Pathology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada

Reprint requests to: Michael Shier, MD, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, Room B6 10, Toronto, Ontario, Canada M4N 3M5. E-mail:

©2010The American Society for Colposcopy and Cervical Pathology