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Lichen Sclerosus: Treatment and Follow-Up at the Departments of Gynaecology and Dermatology

van der Avoort, Irene A.M. MD, MSc1; Tiemes, Demia E.M. MD2; van Rossum, Michelle M. PhD, MD2; van der Vleuten, Carine J.M. PhD, MD2; Massuger, Leon F.A.G. PhD, MD1; de Hullu, Joanne A. PhD, MD1

Journal of Lower Genital Tract Disease: April 2010 - Volume 14 - Issue 2 - p 118-123
doi: 10.1097/LGT.0b013e3181c4bfe6
Original Articles

Objective: To compare the treatment and follow-up of patients with lichen sclerosus (LS) at the departments of Gynaecology and Dermatology at the Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands, to evaluate the need for a multidisciplinary vulvar clinic.

Materials and Methods: Treatment and follow-up data of all women with histologically proven (between January 1995 and January 2001) anogenital LS visiting the outpatient clinics of the departments of Obstetrics & Gynaecology and Dermatology were collected (last date of follow-up: January 2008).

Results: Eighty-four patients with LS were included in this study, 10 patients (12%) of which were treated by both specialties. At the Gynaecology department, LS patients more often received surgical treatment, topical estrogens, and lidocaine ointment, whereas at the Dermatology department, local class 2/3 corticosteroids were more often prescribed. Follow-up frequencies were similar in both specialties and took place at 3 to 4 visits in the first year and at least once a year afterward. One patient developed vulvar squamous cell carcinoma. This patient had withdrawn from follow-up and had her condition diagnosed with carcinoma 74 months after the LS had been diagnosed.

Conclusions: Although no hospital guidelines existed, management of patients with LS agreed with current recommendations in the literature, although differences in secondary and supportive therapy existed owing to differences in expertise. The relatively high percentage of patients treated by both specialties with a high frequency of visits emphasizes the need for a multidisciplinary clinic for vulvar disease.

1Department of Obstetrics & Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; and 2Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Reprint requests to: Irene A.M. van der Avoort, MD, MSc, Department of Obstetrics & Gynaecology (791), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. E-mail:

©2010The American Society for Colposcopy and Cervical Pathology