This study aimed to determine the prevalence
of lymphovascular invasion
(LVSI) in the cervix and its survival impact on women with early-stage cervical cancer
specimens who underwent radical hysterectomy.
Materials and Methods. Lymphovascular invasion
was reviewed in 107 cases of cervical cancer
stages IB1 and IIA and compared with the original pathological examination. In addition, the relapse impact
was calculated appropriately for each patient and compared with the presence of LVSI.
Results. Lymphovascular invasion
in the cervix was detected in 17.8% (9/107) of the cases (95% CI = 11.37-25.87) in the original pathological examination, and when the samples were reviewed specifically looking for this finding in this study, 74.8% (80/107) of the cases (95% CI = 65.9-82.31) were positive. Patients were followed for a mean of 4.87 ± 2.66 years, and tumor relapse was not different among patients with (27.5%; 22/80) and without (7.4%; 2/27) LVSI (p
=.058), although a strong tendency was demonstrated.
The LVSI prevalence
is underestimated in routine pathological examinations, and its rate increases considerably when carefully reviewed. The association between its presence and a worse prognosis needs further investigation.