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Vaginal Solitary Fibrous Tumor: A Case Report with Recurrence after Incomplete Excision

Iyengar, Pratibha MD1; Ismiil, Nadia D. MD2; Gerber, David MD3; Khalifa, Mahmoud A. MD2

Journal of Lower Genital Tract Disease: January 2007 - Volume 11 - Issue 1 - p 50-54
doi: 10.1097/01.lgt.0000230205.73365.5e
Case Report

Objective. Primary solitary fibrous tumors (SFTs) of the female genital tract are exceedingly rare. We report a spindle cell tumor of the vagina with features consistent with a SFT in a 52-year-old woman.

Materials and Methods. The original tumor was studied with the appropriate panel of immunohistochemical stains. The first recurrence of the tumor was 10 months after its original incomplete excision, and a second recurrence occurred 29 months later. Both recurrences were analyzed using the same immunohistochemical panel.

Results. After considering several related differential diagnoses, the diagnosis of SFT was made based on the morphological and immunophenotypic features.

Conclusion. To the best of our knowledge, this is the third case of vaginal SFT in the English literature, with 2 recurrences after incomplete excision.

This is a report of a vaginal solitary fibrous tumor in a 52-year-old woman, which recurred twice after its original incomplete excision.

1Department of Pathology, Credit Valley Hospital, Mississauga, Ontario, Canada; 2Department of Pathology, Sunnybrook and Women's College Health Sciences Center, and 3Toronto Gynecology and Colposcopy, Toronto, Ontario, Canada

Reprint requests to: Mahmoud Khalifa, MD, Department of Pathology, Sunnybrook and Women's College Health Sciences Center, Room E4-16, 2075 Bayview Avenue, Toronto, Ontario, Canada. E-mail:

©2007The American Society for Colposcopy and Cervical Pathology