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Lymphoepithelioma-Like Carcinoma of the Vulva

Niu, Weiwei MD1; Heller, Debra S. MD1; D'Cruz, Cyril MD2

Journal of Lower Genital Tract Disease: July 2003 - Volume 7 - Issue 3 - p 184-186
Original Articles

Lymphoepithelioma is well known in the nasopharyngeal region. Although this neoplasm is well described in a variety of extranasal sites, where it is termed lymphoepithelioma-like carcinoma, this is only the second report of this neoplasm originating in the vulva reported in the literature. These lesions are reported to be less aggressive in extranasal sites. A 40-year-old woman presented with a lymphoepithelioma-like carcinoma of the vulva, diagnosed by excisional biopsy, which had been present for 1 month. The lesion persisted with ipsilateral lymph node involvement 4 months after initial resection, when the patient returned for definitive surgery. Lymphoepithelioma-like carcinoma can occur rarely in the vulva, and may behave aggressively.

1Departments of Pathology and Laboratory Medicine, UMDNJ-New Jersey Medical School, Newark, NJ; and 2Newark-Beth Israel Medical Center, Newark, NJ

Reprint requests to: Debra S. Heller, MD, Department of Pathology-UH/E158, UMDNJ-New Jersey Medical School, PO Box 1709, Newark, NJ 07101. E-mail:

©2003The American Society for Colposcopy and Cervical Pathology