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Executive summary of the joint position paper on renal denervation of the Cardiovascular and Interventional Radiological Society of Europe and the European Society of Hypertension

Moss, Jonathan G.; Belli, Anna-Maria; Coca, Antonio; Lee, Michael; Mancia, Giuseppe; Peregrin, Jan H.; Redon, Josep; Reekers, Jim A.; Tsioufis, Costas; Vorwerk, Dierk; Schmieder, Roland E.

doi: 10.1097/HJH.0000000000001147

Renal denervation (RDN) was reported as a novel exciting treatment for resistant hypertension in 2009. An initial randomized trial supported its efficacy and the technique gained rapid acceptance across the globe. However, a subsequent large blinded, sham arm randomized trial conducted in the USA (to gain Food and Drug Administration approval) failed to achieve its primary efficacy end point in reducing office blood pressure at 6 months. Published in 2014 this trial received both widespread praise and criticism. RDN has effectively stopped out with clinical trials pending further evidence. This joint consensus document representing the European Society of Hypertension and the Cardiovascular and Radiological Society of Europe attempts to distill the current evidence and provide future direction and guidance.

aInterventional Radiology, North Glasgow University Hospitals, Glasgow

bDepartment of Radiology, St George's Hospital, London, United Kingdom

cHypertension and Vascular Risk Unit, Department of Internal Medicine, Hospital Clínic (IDIBAPS), University of Barcelona, Barcelona, Spain

dDepartment of Radiology, Beaumont Hospital, Dublin 9, Ireland

eUniversity of Milano-Bicocca, Milano, Italy

fDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague 4, Czech Republic

gResearch Institute INCLIVA, University of Valencia and CIBERObn, ISCIII, Madrid, Spain

hUniversity of Amsterdam, Department of Radiology, Academic Medical Centre Amsterdam, Amsterdam, The Netherlands

iNational and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece

jInstitute of Radiology, Klinikum Ingolstadt, Ingolstadt

kUniversity Hospital Erlangen, Nephrology and Hypertension, Erlangen, Germany

Correspondence to Prof Jonathan G. Moss, Interventional Radiology Unit, North Glasgow Hospitals, Gartnavel General Hospital, 1053 Great Western Road, Glasgow, United Kingdom. Tel: +44 0 1412113115; e-mail:

Received 13 September, 2016

Accepted 13 September, 2016

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