S-07-1: TARGETING SENESCENT CELLS AS A NOVEL THERAPEUTIC STRATEGY FOR AGE-ASSOCIATED DISEASE : Journal of Hypertension

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ORAL: CELLULAR SENECENCE AND SENOLYSIS

S-07-1: TARGETING SENESCENT CELLS AS A NOVEL THERAPEUTIC STRATEGY FOR AGE-ASSOCIATED DISEASE

Minamino, Tohru1

Author Information
Journal of Hypertension 41(Suppl 1):p e24, January 2023. | DOI: 10.1097/01.hjh.0000912928.48160.b5
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Abstract

References:

  • 1) Suda M, Minamino T. Senolytic vaccination improves pathological aging. Nat Aging. 2021; 1: 1117-1126.
  • 2) Yokoyama M, Minamino T. Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity. Cell Rep 2014; 7: 1691-1703.
  • 3) Shimizu I, Minamino T. Semaphorin-induced inflammation contributes to insulin resistance in dietary obesity. Cell Metab 2013; 18: 491-504.
  • 4) Naito AT, Minamino T, Komuro I. Complement C1q activates canonical wnt signaling and promotes age-related phenotypes. Cell 2012; 149: 1298-1313.
  • 5) Shimizu I, Minamino T. p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. Cell Metab 2012; 15: 51-64.
  • 6) Minamino T, Komuro I. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med 2009; 15: 1082-1087.
  • 7) Sano M, Minamino T∗, and Komuro I. p53-induced Inhibition of Hif-1 Causes Cardiac Dysfunction during Pressure Overload. Nature 2007 446: 444–448. (∗Co-first author)
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