aUniversity Hospital Erlangen, Department of Nephrology and Hypertension, Erlangen
bDepartment of Internal Medicine, Universitätsklinikum des Saarlandes, Saarland, University, Homburg/Saar, Germany
cUniversity of Milano-Bicocca, Milan, Italy
dUniversité de Paris, INSERM, AP-HP, Hypertension Department and DMU CARTE, Hôpital Européen Georges-Pompidou Paris, France
eUniversitätsklinikum des Saarlandes, Klinik für Innere Medizin III, Saarland University (Kardiologie, Angiologie und Internistische Intensivmedizin), Homburg/Saar, Germany
fNational and Kapodistrian University of Athens, 1st Cardiology Clinic, Hippocratio Hospital, Athens, Greece
gDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University of Medicine, Tochigi, Japan
hDepartment of Internal Medicine, Maastricht University Medical Center & Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands
iBarts NIHR Biomedical Research Centre, William Harvey Research Institute, Queen Mary University of London, London, UK
jDepartment of Nephrology and Hypertension, Paracelsus Medical University, Nürnberg, Germany
kDepartment of Cardiovascular Medicine, Princess Grace Hospital, Monaco and Research Unit Toulouse University, Centre National de la Recherche Scientifique UMR 5288, Toulouse, France
lPole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, and Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
mInterventional Cardiology Department, Heart Center, Policlinico di Monza, Monza, Italy and ESH Excellence Center, Istituto Clinico Verano Brianza, Verano Brianza, Italy
nDobney Hypertension Centre, School of Medicine - Royal Perth Hospital Unit, Medical Research Foundation, Faculty of Medicine, Dentistry & Health Sciences, The University of Western Australia, Perth Australia and Departments of Cardiology and Nephrology, Royal Perth Hospital, Perth, Western Australia, Australia
oCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany
pNational and Kapodistrian University of Athens, 1st Cardiology Clinic, Hippocratio Hospital, Athens, Greece
Correspondence to Roland E. Schmieder, MD, Head of the Clinical Research Center, Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich Alexander University Erlangen/Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany. Tel: +49 9131 85 39002; fax: +49 9131 85 36215; e-mail: [email protected], [email protected]
Abbreviations: BP, blood pressure; eGFR, estimated glomerular filtration rate; GSR, Global Symplicity Registry; RCT, randomized clinical trial; RDN, renal denervation; SNS, sympathetic nervous system
Received 6 June, 2021
Accepted 7 June, 2021