aDepartment of Pharmacology, School of Pharmacy, University of Granada
bGene Regulation in Cardiovascular Remodeling and Inflammation Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid
cCIBER-Enfermedades Cardiovasculares (CiberCV)
dInstituto de Investigación Biosanitaria de Granada (ibs.GRANADA)
eDepartment of Pathological Anatomy, School of Medicine, University of Granada
fCentro de Investigaciones Biomédicas (CIBM), Granada, Spain
Correspondence to Juan Duarte, Department of Pharmacology, School of Pharmacy, University of Granada, 18071 Granada, Spain. Tel: +34 958241791; fax: +34 958248264; e-mail: [email protected]
Abbreviations: ACh, acetylcholine, anti-dsDNA, plasma anti-double-stranded DNA; Apo, apocynin; DAPI, 4,6-diamidino-2-phenylindoledichlorohydrate; DHE, dihydroethidium; eNOS, endothelial NO synthase; HR, heart rate; IFN, type I interferons; IMQ, imiquimod; l-NAME,
N(ω)-nitro-l-arginine methyl ester; M/L, media–lumen ratio; MABP, mean arterial blood pressure; MCSA, media cross-sectional area; MT, media thickness; NADPH, nicotinamide adenine dinucleotide phosphate; nIL-17, IL-17-neutralizing antibody; NO, nitric oxide; O2−
, superoxide anions; RLU, relative luminescence units; RT-PCR, reverse transcriptase-PCR; SLE, systemic lupus erythematosus; SNP, sodium nitroprusside; TLR7, toll-like receptor 7; TLR9, toll-like receptor 9; TLRs, toll-like receptors; VCAM-1, vascular cell adhesion molecule-1
Received 9 May, 2019
Revised 24 December, 2019
Accepted 24 December, 2019
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