REVIEWS AND META-ANALYSESLaparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for 5-year hypertension remission in obese patients a systematic review and meta-analysisCliment, Elisendaa,b; Goday, Alberta,b,c,d; Pedro-Botet, Juana,b,c; Solà, Ivane,f; Oliveras, Annag,h; Ramón, José Manuelc,i; Flores-Le Roux, Juana Antoniaa,b,c; Checa, Miguel Ángelj,k,l; Benaiges, Davida,b,cAuthor Information aDepartment of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítim o bDepartment of Medicine, Universitat Autònoma de Barcelona cInstitut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona dCiberOBN. Instituto de Salud Carlos III. Avda Monforte de Lemos, Madrid eIberoamerican Cochrane Centre, Biomedical Research Institute Sant Pau (IIB Sant Pau), Carrer Sant Antoni Maria Claret, Barcelona fCIBER Epidemiología y Salud Pública (CIBERESP). Avda Monforte de Lemos, Madrid gHypertension Unit, Nephrology Department hDepartment of Nephrology iDepartment of General Surgery jDepartment of Obstetrics and Gynecology, Hospital del Mar; Paseo Marítimo kDepartment of Pediatrics, Obstetrics and Ginecology and Public Health, Universitat Autònoma de Barcelona, Campus Universitari Mar lGrup de Recerca en Infertilitat de Barcelona (GRI-BCN), (SGR527), Dr Aiguader, Barcelona, Spain Correspondence to Dr David Benaiges, PhD, Department of Endocrinology, Hospital del Mar, Paseo Marítimo, 25-29, E-08003 Barcelona, Spain. Tel: +34 932483902; fax: +34 932483254; e-mail: email@example.com Abbreviations: GB, Roux-en-Y gastric bypass; HTN, hypertension; SG, sleeve gastrectomy Received 20 June, 2019 Revised 2 August, 2019 Accepted 21 August, 2019 Journal of Hypertension: February 2020 - Volume 38 - Issue 2 - p 185–195 doi: 10.1097/HJH.0000000000002255 Buy Metrics Abstract Controversial results exist on mid-term effects of Roux-en-Y gastric bypass and sleeve gastrectomy on hypertension remission. The aim of the present systematic review was to study 5-year hypertension remission after both procedures. One-year hypertension remission and SBP and DBP pressure change at 1 and 5 years after both surgical techniques were also evaluated. We searched MEDLINE, EMBASE and The Cochrane Central Register of Controlled Trials (CENTRAL). Thirty-two articles were included (six randomized controlled trials, 18 cohort and eight case–control studies). The proportion of patients with hypertension remission was greater for those treated with gastric bypass compared with sleeve gastrectomy at 5 years (RR = 1.26, 95% CI = 1.07–1.48) and 1 year (RR = 1.14, 95% CI = 1.06–1.21). Gastric bypass and sleeve gastrectomy did not differ in terms of SBP or DBP change. Patients treated with gastric bypass present a higher hypertension remission rate at 1 and 5 years. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.