aLaboratory of Animal Reproduction, Department of Animal Science, Tokyo University of Agriculture, Atsugi, Kanagawa
bDepartment of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, Tochigi, Japan
Correspondence to Koumei Shirasuna, PhD, Laboratory of Animal Reproduction, Department of Animal Science, Tokyo University of Agriculture, 1737 Funako, Atsugi, Kanagawa 234-0034, Japan. Tel: +81 46 270 6588; fax: +81 46 247 4338; e-mail: [email protected]
Abbreviations: cfDNA, cell-free DNA; cffDNA, cf-fetal DNA; cGAS, protein cyclic GMP-AMP synthase; DAMP, danger-associated molecular pattern; HUVEC, human umbilical vein endothelial cells interleukin; IFI16, interferoninducible protein 16; IFN, interferon; IL, interleukin; LDH, lactate dehydrogenase; sEng, soluble endoglin; sFlt1, soluble fms-like tyrosine kinase; STING, the stimulator of interferon genes; TLR9, toll-like receptor
Received 18 December, 2018
Revised 27 April, 2019
Accepted 10 July, 2019