Physiological adaptive changes influence significantly cardiovascular system that has to act under greater loading conditions. Taking into account the fact that arterial hypertension (AH) is among mainreasons of early delivery and complications, importance of early detection of AH in pregnancy, we estimated diurnal blood pressure profiles and vegetative system's influence over cardiovascular system in pregnant women with different gestation terms comparing those after delivery.
62 females were examined, age - 19 to 36 (averagely – 25,6 ± 7,2 years). 48 had confirmed pregnancy (main group) and had no history of any somatic illnesses before pregnancy, 14 - healthyy women with childbearing potential. Ambulance blood pressure monitoring and ECG Holter monitoring were conducted to them. Measurements were carried out in 1st, 2nd and 3rd trimesters of preggnancy with follow up done at 6th ewek after delivery. All results were statistically approved.
25% of main group patients (subgroup A) had mild Blood pressure (BP) increase at 1st visit (systolic- 13,44%, diastolic 9,21%(p < 0,05). 32% of them had genetic predisposition to AH and increased body mass index. In rest (subgroup B), systolic BP was usual, and diastolic - decreased (5,2%). No statistically significant changes were detected in 2nd trimester. In 3rd trimester, AH progressed to preeclapsia in 22% patients of subgroup A, and was detected in 12% patients of subgroup B. Proteiuuria and oedema were detected in 54% of patients of subgroup A, In rest, both systolic abd diastolic pressure were mildly decreased. Majoriity patients demonstrated recovery 6 weeks after delivery, but in 4.8% AH persisted.
Physiological decrease of BP in specific for 1st and 3rd trimesters of physiological pregnancy