ORIGINAL PAPERS: EpidemiologyNeck circumference and prehypertension the cardiometabolic risk in Chinese studyLiang, Juna,*; Wang, Yua,*; Dou, Lianjuna; Li, Hongyana; Liu, Xuekuia; Qiu, Qinqinb; Qi, Luc,d Author Information aDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College, Xuzhou Institute of Medical Sciences, Xuzhou Institute of Diabetes, Affiliated Hospital of Southeast University bXuzhou Medical College, Xuzhou, Jiangsu, China cDepartment of Nutrition, Harvard School of Public Health dChanning Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA *Both Jun Liang and Yu Wang contributed equally to this work. Correspondence to Dr Lu Qi, MD, PhD, Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA. Tel: +1 617 432 4116; fax: +1 617 432 2435; e-mail: [email protected] Abbreviations: HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; TC, total cholesterol; WHR, waist-to-hip ratio Received 21 January, 2014 Revised 26 August, 2014 Accepted 26 August, 2014 Journal of Hypertension: February 2015 - Volume 33 - Issue 2 - p 275-278 doi: 10.1097/HJH.0000000000000396 Buy Metrics Abstract Background: We have previously found that neck circumference was related to insulin resistance, a risk factor for hypertension in Chinese. Little is known about whether high neck circumference is associated with elevated blood pressure. Method: The study samples were from a community-based health examination survey in central China. In total, 1709 men and women with neck circumference measurement were included. We analysed the associations between neck circumference and the risk of prehypertension. Results: Although neck circumference was strongly associated with SBP/DBP in a univariate analysis, it was no longer associated with SBP and the association was much weaker with DBP when the association was adjusted for BMI or waist circumference. Similarly, high neck circumference was significantly related to an increased risk of prehypertension [odds ratio 1.254; 95% confidence interval (95% CI) 1.171–1.343] in a univariate analysis, and the association became marginal in models further adjusting for BMI or waist. Conclusion: Our data suggest that neck circumference as predictor for prehypertension is not obvious given the moderate improvement of disease prediction. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.