Review articleBaroreceptor reflex pathways and neurotransmitters: 10 years onPilowsky, Paul M.; Goodchild, Ann K. Author Information Hypertension and Stroke Research Laboratories, Departments of Physiology and Neurosurgery, University of Sydney, Royal North Shore Hospital, Sydney, New South Wales, Australia. Tel: +61 29926 8080; fax: +61 29926 6483; e-mail [email protected] Sponsorship: This work was supported by grants NHMRC (980077, 211023, 211196), NHF (G00S0716, G99S0472), NSHRF (17-00/01, 14-00/01), Garnett Passe and Rodney Williams Memorial Foundation. Correspondence and requests for reprints to Professor Paul Pilowsky, Hypertension and Stroke Research Laboratories, Block 3, Ground Floor, Royal North Shore Hospital, St Leonards, 2065, Australia. Tel: +61 2 9926 8080; fax: +61 2 9926 6483; email: [email protected] Received 17 April 2002 Revised 24 May 2002 Accepted 27 May 2002 This review was presented in part as an Invited Lecture at the Chalmer's Symposium in Sydney, Australia on 11 December 2001, and is dedicated to John Chalmers. Journal of Hypertension 20(9):p 1675-1688, September 2002. Buy Abstract The central nervous system plays a critical role in the management of blood flow to the tissues and its return to the heart and lungs. This is achieved by a complex interplay of neural efferent pathways, humoral mechanisms and afferent pathways. In this review, we focus on recent progress (within the past 10 years) that has been made in the sympathetic control of arterial blood pressure with a special emphasis on the role of baroreceptor mechanisms and central neurotransmitters. In particular, we focus on new features since 1991, such as neurotransmission in the nucleus tractus solitarius, the role of neurons in the most caudal part of the ventrolateral medulla oblongata and the increasing understanding of the exquisite control of different sympathetic pathways by different neurotransmitter systems. © 2002 Lippincott Williams & Wilkins, Inc.