Rapid communication: PDF OnlyActivity of protein kinase C in erythrocytes in primary hypertensionKravtsov, Gennadi M.; Dulin, Nikolai O.; Postnov, Yuvenali V. Author Information From the Central Research Laboratory of the Ministry of Public Health of the USSR, Timoshenko av. 23, Moscow 121359, USSR Journal of Hypertension: November 1988 - Volume 6 - Issue 11 - p 853-857 Buy Abstract The activity of protein kinase C and A was studied in the erythrocytes of patients with essential hypertension (EH) and in spontaneously hypertensive rats (SHR, Okamoto—Aoki strain). Protein kinase C activity was also studied in the erythrocytes of patients with hypertension of renal origin. Protein kinase C activity in the lysate of erythrocytes of patients with EH and in SHR was found to be increased 1.6–2.0-fold as compared to that in normotensive controls. No notable differences in protein kinase A activity were observed between hypertensive and normotensive groups. In erythrocytes of patients with renal hypertension, no notable changes in protein kinase C activity were revealed. © Lippincott-Raven Publishers.
